Making medicine ingredients in Nigeria
World Class Quality, Indigenously African
This page describes Egbogi Therapeutics' plan to build local active pharmaceutical ingredient (API) manufacturing in Nigeria, starting with paracetamol.
ROADMAP
From pilot to industrial scale
Supply security
Local production could reduce dependence on imported active ingredients and buffer against global supply disruptions.
Cost potential
Manufacturing closer to formulation sites could lower logistics and import-related expenses over time.
Quality oversight
Domestic facilities could enable closer oversight of production quality and supply chain integrity.
Skills and jobs
A local API industry could create skilled technical jobs and build pharmaceutical manufacturing expertise in Nigeria.
Health system resilience
Reliable local supply of essential APIs could strengthen the health system's ability to respond to demand.
WHY PARACETAMOL FIRST
A familiar medicine, a clear starting point
Paracetamol is one of the most widely used medicines in Nigeria, and its active ingredient is currently imported. Starting here gives the manufacturing platform a clear, well understood product to build around.
✓ One of the most widely used medicines in the country
✓ Active ingredient currently imported, so the gap is easy to see
✓ A well understood product to prove the platform on
ROADMAP
From pilot to industrial scale
Three stages, each with a plain status. The bar in each card shows relative batch size only; it is not a progress bar, and no stage is presented as already in production.
20 kg pilot
Modular microwave reactor
A modular microwave-assisted reactor system, built and in development.
500 kg pilot scale
Scale-up milestone
A pilot-scale reactor in development, to test scale-up from the pilot system.
Commercial lines
Industrial scale
Industrial-scale manufacturing of active pharmaceutical ingredients in Nigeria.
MICROWAVE PROCESS
Faster, cleaner reactions, built to scale
The process uses microwave-assisted synthesis, developed by Nigerian scientists and engineers, to make reactions faster and cleaner, and to scale from pilot batches to industrial production. The technology is planned and in development.
Raw material feed
Ingredients enter the system measured and checked.
Microwave reactor
Microwave energy drives the reaction, faster and cleaner.
Cooling and quench
The reaction is cooled and stopped safely.
Filtration and wash
The product is separated and washed clean.
Drying and packing
Dried, packed and documented, batch by batch.
QUALITY AND COMPLIANCE
Quality is built into the process
The manufacturing platform follows GMP principles, with attention to the checks below at every batch.
✓ GMP principles across the platform
✓ Attention to NAFDAC requirements
✓ Pharmacopeial standards
✓ Impurity profiling
✓ Full batch documentation
